Chelate Labeling Reagent
Product codeD550 Dithiobis(C2-NTA)
Chemical name3,3'-Dithiobis[N-(5-amino-5-carboxypentyl)propionamide-N',N'-diacetic acid] dihydrOchloride
|Unit size||Price||Item Code|
Dithiobis(C2-NTA) is utilized for the modification of a gold surface to introduce NTA groups that can bind most heavy metal ions. It forms SAMs similar to the other alkanethiols. The SAMs prepared using Dithiobis(C2-NTA) are highly unidirectional due to its alkyl chain interactions. Ni(II)-NTA chelates are commonly used for Histidine-tagged (His-tag) protein purification or separation. Therefore, Ni(II)-NTA-coated gold can be used for His-tag protein analyses. Dithiobis(C2-NTA) is soluble in water and alcohol. It is also referred to as disulfide-NTA in some papers.
1)M. Murata, C. Gouda, K. Yano, S. Kuroki, T. Suzutani and Y. Katayama, "Piezo electric sensor for endocrine-disrupting chemicals using receptor-co-factor interaction",Anal. Sci., 2003, 19, 1355.
Handling and storage condition
|Appearance：||White to slightly yellow powder or crystal|
|Purity (Absorbance)：||≧ 95.0 % (as anhydrous)|
|Solubility in water：||To pass test (clear, colorless to slightly yellow)|
|Water content：||≦ 10.0 %|
|Nitrogen substitution, Protect from moisture|