Surface Chemistry


Biosensor means the chemical sensor available for the molecular recognition system of the the organism. It can be detected by converting into electrical signals to substrate-specific variations due to enzyme reaction, antigen-antibody reaction, ion channel, and so on. Since glucose sensor was developed in 1967 that is supported glucose oxidase by gel on the electrode, various biosensor has been developed.
There are three points to manufacture the biosensor: 1) select the "receptor" to immobilize on the substrate, 2) choose the "immobilization method" for that, 3) select the "detecting method" that will capture the variation due to the interaction of the receptor.
Dojindo offers SAM reagents, cross-linker reagents, activation reagents, and biotinylation reagents available for the "Immobilization method", and these reagents have been used for developing biosensors.

Amino alkanethiol SAM Formation Reagent (one-shot type able to prepare an optimum SAM solution)
Products Products
11-Amino-1-undecanethiol, hydrochloride Biotin-SAM Formation Reagent
16-Amino-1-hexadecanethiol, hydrochloride Carboxylic acid-SAM Formation reagent
8-Amino-1-octanethiol, hydrochloride NTA-SAM Formation Reagent
6-Amino-1-hexanethiol, hydrochloride

Carboxy alkanethiol Amine reactive
Products Products
15-Carboxy-1-pentadecanethiol Amine Coupling Kit
10-Carboxy-1-decanethiol Dithiobis(succinimidyl undecanoate)
7-Carboxy-1-heptanethiol Dithiobis(succinimidyl octanoate)
5-Carboxy-1-pentanethiol Dithiobis(succinimidyl hexanoate)

Hydroxy alkanethiol Carboxylate coating
Products Products
16-Hydroxy-1-hexadecanethiol 10-Carboxydecyl disulfide
11-Hydroxy-1-undecanethiol 7-Carboxyheptyl disulfide
8-Hydroxy-1-octanethiol 5-Carboxypentyl disulfide
6-Hydroxy-1-hexanethiol 4, 4'- Dithiodibutyric acid

NTA modification Sufobetaine alkanethiol
Products Products
Dithiobis(C2-NTA) Sulfobetaine3-undecanethiol

Electrochemical reaction Amide alkanethiol
Products Products
11-Ferrocenyl-1-undecanethiol 10-Amido-1-decanethiol
8-Ferrocenyl-1-octanethiol 7-Amido-1-heptanethiol
6-Ferrocenyl-1-hexanethiol 5-Amido-1-pentanethiol

Phosphonic Acid SAM PEG alkanethiol
Products Products
11-AUPA Amino-EG6-undecanethiol, hydrochloride
10-CDPA Amino-EG6-hexadecanethiol, hydrochloride
11-HUPA Carboxy-EG6-undecanethiol
ODPA Carboxy-EG6-hexadecanethiol
M-EG3-UPA Hydroxy-EG6-undecanethiol
FOPA Hydroxy-EG6-hexadecanethiol
FDPA Hydroxy-EG3-undecanethiol
FHPA Hydroxy-EG3-hexadecanethiol