H2S Donor

Chemical Name: (4-Methoxyphenyl)morpholinylphosphinodithioic acid, morpholine salt
CAS: 106740-09-4

Appearance: White to slightly yellow powder
Purity: ≥95.0% (HPLC)
MW: 376.47, C15H25N2O3PS2

Storage Condition: 0-5℁E/font>
Shipping Condition:
ambient temperature

Product Description
GYY4137 is one of the synthetic hydrogen sulfide donors derived from Lawsson’s reagent. It is water-soluble and releases H 2S very slowly by hydrolysis in aqueous solutions. GYY4137 has shown distinct cellular effects such as anti-hypertensive, anti-atherosclerotic and anti-tumor activities in several reports.

Fig. 1 H2S Releasing Mechanism of GYY4137


Fig. 2 H2S Releasing Curve of GYY4137 in PBS (100 μM)


1. L. Li, M. Whiteman, Y. Y. Guan, K. L. Neo, Y. Cheng, S. W. Lee, Y. Zhao, R. Baskar, C- H. Tang and P. K. Moore,Circulation, 2008, 117, 2351.
2. Z. Liu, Y. Han, L. Li, H. Li, G. Meng, X. Li, M. Shirhan, M. T. Peh, L. Xie, S. Zhou, X. Wang, Q. Chen, W. Dai,C-H. Tang, S. Pan, P.K. Moore, and Y. Ji, Br J Pharmacol.,2013, 169, 1795.
3. Z. W. Lee, J. Zhou, C-S Chen, Y. Zhao, C-H. Tan, L Li, P. K. Moore and L-W. Deng, PLoS One., 2011, 6, e21077.

Item # Description/Size Availability Qty Break Price Quantity
10 mg
8-14 business days 1 $64.00

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