Chemical Name: 3',6'-Di(O-thiosalicyl)fluorescein
Appearance: White to pale yellow powder or solid
Purity: ≧ 90.0 %
Storage Condition: 0-20°C, protect from light
Shipping Condition: Ambient temperature
It becomes obvious that there are a lots of molecules
containing sulfane sulfurs such as persulfides and polysulfides in living organism.
These molecular species are involved in production, storage and release of hydrogen
sulfide, which is recognized as an important physiological mediator.
Furthermore, recent studies reveal that persulfides and polysulfides may
control intracellular signal transduction through
SSP4 (Sulfane Sulfur Probe 4) is a novel fluorescent
probe to detect sulfane sulfurs selectively. SSP4 itself is non-fluorescent,
but it emits strong green fluorescence when it reacts with sulfane sulfurs.
Thus, SSP4 enables high sensitive fluorescence detection and imaging of sulfane
Fig. 1 Chemical Reaction with sulfane sulfer
Fig. 2 Fluorescence spectrum (Em: 482nm/Ex: 515nm)
species containing sulfane sulfurs:
Fig. 3 The formation of sulfane sulfer in vivo changes due to reduction/oxidation and translation
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