Storage Condition: 0-5°C
Shipping Condition: Ambient temperature
It becomes obvious that there are a lot of molecules
containing sulfane sulfurs such as persulfides and polysulfides in living organism.
These molecular species are involved in production, storage, and release of
hydrogen sulfide, which is recognized as an important physiological mediator.
Furthermore, recent studies reveal that persulfides and polysulfides may
control intracellular signal transduction through
proteins, and function
in vivo as anti-oxidants which have much higher
reducing activity than glutathione in reduced form or cysteine.
Sodium polysulfides (Na2Sn) are sulfane sulfur donors
which have simple structures, and exist as hydrogen polysulfides in an aqueous
solution depending on pH. These reagents are necessary to for research and
analysis of sulfane
Fig. 1 Chemical
species containing sulfane sulfurs
Characteristics of polysulfides:
Fig. 2 Structures of
Sodium polysulfides (Na
2Sn) and the pKa values.
Kimura, Y. Mikami, K. Osumi, M. Tsugane, J. Oka, and H.
Kimura, "Polysulfides are possible H
molecules in rat brain",
FASEB J., 2013, 27,
2) S. Koike, Y. Ogasawara, N. Shibuya, H. Kimura, and
K. Ishii, "Polysulfide exerts a protective effect against
cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in
FEBS Lett., 2013, 587,