• Easily forms carboxy-terminated monolayers on gold
  • Suppress non-specific binding

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    Appearance: Colorless or pale yellow liquid

    Storage Condition: 0-5°C

    Shipping Condition: Ambient temperature

    Product Description
    Carboxylic acid-SAM Formation Reagent is used to prepare carboxylic acid- terminated self-assembled monolayers (SAMs) on gold surfaces as biosensors detected by QCM (Quartz Crystal Microbalance), SPR (Surface Plasmon Resonance), and electrochemical analysis. Coupled with carboxyl group activation method using NHS/WSC, carboxylic acid-SAM can be used as an interface to immobilize proteins or peptides and other ligands on gold surfaces (Fig. 1). In general, carboxylic acid-SAM provides some non-specific binding because of its negative charge. However, surfaces prepared using -carboxylic acid-SAM Formation Reagent presents less non-specific binding than thiose commonly prepared with carboxylic acid-SAM (Fig. 2).


    Fig. 1 A biosensor construction by Carboxylic acid-SAM Formation Reagent


    Fig. 2 Comparison of non-specific binding between carboxylic acid-SAM prepared with carboxylic acid-SAM Formation Reagent and commonly prepared SAM
    Item # Description/Size Availability Qty Break Price Quantity
    C488-10
    1 µmol x 3
    8-14 business days 1 $213.00

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