Application: SAM preparation, dilution of functional alkanethiols

 
MSDS
Chemical Name: 16-Hydroxy-1-heptadecanethiol
CAS: 114896-32-1


Appearance:
White or slightly yellowish crystalline powder
Purity: ≥90.0% (HPLC)
MW:
274.51, C16H34OS

Storage Condition: ambient temperature
Shipping Condition: ambient temperature


Structural Formula


Product Description
Hydroxyalkanethiols are utilized as dilution reagents on a gold surface to control the density of reactive groups, or as blocking agents to prevent non-specific binding of analytes on the surface. Newly developed 16-Hydroxy-1-hexadecanethiol has a 16-carbon chain which is the longest alkanethiol available in the market among hydroxyalkanethiols. In all, there are a total of 6 different hydroxyalkanethiols including Hydroxy-EG6-undecanethiol and Hydroxy-EG3-undecanethiol available for gold surface modification. 16-Hydroxy-1-hexadecanethiol is used to prepare a homogeneous and highly oriented SAM when 16-Amino-1-hexadecanethiol or 15-Carboxy-1-pentadecanethiol is applied. Herne and his co-workers fabricated mixed SAMs of thiol-derivatized singlestranded DNA (HS-ss-DNA) and 6-Hydroxy-1-hexanethiol on a gold surface that prevented non-specific adsorption of HS-ss-DNA. Perez-Luna and others made mixed SAMs of biotin-terminated thiol and 11-hydroxy-1-undecanethiol on a gold surface. They prevented non-specific adsorption of wild type streptavidin and streptavidin mutants. Dubrovsky and coworkers controlled the non-specific adsorption of protein on the surface of gold-coated silicagel using 11-Hydroxy-1-undecanethiol. They mentioned the usefulness of gold-coated silica gel for the preparation of well-defined, surface-functionalized supports for biological assay.

Item # Description/Size Availability Qty Break Price Quantity
H394-10
10 mg
8-14 business days 1 $146.00

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