Application: SAM preparation, carboxylate coating,
                      and hydrophilic surface

 
MSDS
Chemical Name: 20-(11-Mercaptoundecanyloxy-3,6,9,12,15,18-hexaoxaeicosanoic acid
CAS: 221222-49-7


Appearance:
White or pale yellow pwoder
Purity: ≥90.0% (HPLC)
MW:
526.73, C25H50O9S

Storage Condition: -20oC, protect from metal
Shipping Condition: ambient temperature



Structural Formula



Product Description
Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Carboxy-EG6-undecanethiol has 6 ethylene glycol units, 11 carbon Atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface suitable for biomaterial-labelings on the surface due to the improved hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays. To prepare a carboxy-EG6-SAM on a gold surface, hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute the number of carboxyl groups according to the density of the molecules being introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin and cytochrome C.

References
1. C. Pale-Grosdemange, E. S. Simon, K. L. Prime, and G. M. Whitesides, Anal. Chem., 1999, 71, 777.
2. A. Subramanian, J. Irudayaraj, and T. Ryan, Biosensors and Bioelectronics, 2006, 21, 998.
3. X. Qian, S. J. Metallo, I. S. Choi, H. Wu, M. N. Liang and G. M. Whitesides, Anal. Chem., 2002, 74, 1805.
4. M. Kyo, K.Usui-Aoki, H. Koga, Anal. Chem, 2005, 77, 7115.
Item # Description/Size Availability Qty Break Price Quantity
C445-10
10 mg
8-14 business days 1 $253.00
C445-12
100 mg
8-14 business days 1 $541.00

*Your estimated shipping date is calculated based on production, payment method, destination, and your shipping option.
For Research Use Only Products