20 Functional Organic Material

Hydroxy-EG6-undecanethiol

Hydroxy-EG6-undecanethiol

Self Assembled Monolayer Reagent

  • Product code
    H355  Hydroxy-EG6-undecanethiol
  • CAS No.
    130727-44-5
  • Chemical name
    11-Mercaptoundecanol hexaethyleneglycol ether
  • MW
    C23H48O7S=468.69
Unit size Price Item Code
10 mg $213.00 H355-10
100 mg $458.00 H355-12
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Chemical Formula

Product Description

Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Hydroxy-EGn-undecanethiol has 3 or 6 ethylene glycol units, 11 carbon atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface that is suitable for biomateriallabelings on the surface. This is due to the improvement of hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays. Hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute Carboxyl -SAM or Amino-SAM according to the density of the molecules be introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin and cytochrome C.

References

Open References

1. C. Pale-Grosdemange, E. S. Simon, K. L. Prime, and G. M. Whitesides, Anal. Chem., 1999, 71, 777.
2. A. Subramanian, J. Irudayaraj, and T. Ryan, Biosensors and Bioelectronics, 2006, 21, 998.
3. X. Qian, S. J. Metallo, I. S. Choi, H. Wu, M. N. Liang and G. M. Whitesides, Anal. Chem., 2002, 74, 1805.
4. M. Kyo, K.Usui-Aoki, H. Koga, Anal. Chem, 2005, 77, 7115.

Handling and storage condition

Specification
Purity (HPLC): ≧ 90.0 %
Appearance: Colorless to pale yellow liquid
NMR spectrum: Authentic
Handling and storage condition
-20°C, Nitrogen substitution
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Product Classification

Product Classification

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