09 Cross-Linking Reagents
20 Functional Organic Material



Chelate Labeling Reagent

  • Product code
    D550  Dithiobis(C2-NTA)
  • CAS No.
  • Chemical name
    3,3'-Dithiobis[N-(5-amino-5-carboxypentyl)propionamide-N',N'-diacetic acid] dihydrOchloride
  • MW
Unit size Price Item Code
10 mg $239.00 D550-10
50 mg $1008.00 D550-12

Quantity may be adjusted within the cart.


Structural Formula

Product Description
Dithiobis(C2-NTA) is utilized for the modification of a gold surface to introduce NTA groups that can bind most heavy metal ions. It forms SAMs similar to the other alkanethiols. The SAMs prepared using Dithiobis(C2-NTA) are highly unidirectional due to its alkyl chain interactions. Ni(II)-NTA chelates are commonly used for Histidine-tagged (His-tag) protein purification or separation. Therefore, Ni(II)-NTA-coated gold can be used for His-tag protein analyses. Dithiobis(C2-NTA) is soluble in water and alcohol. It is also referred to as disulfide-NTA in some papers.


Open References

1)M. Murata, C. Gouda, K. Yano, S. Kuroki, T. Suzutani and Y. Katayama, "Piezo electric sensor for endocrine-disrupting chemicals using receptor-co-factor interaction",Anal. Sci., 200319, 1355.

Handling and storage condition

Appearance: White to slightly yellow powder or crystal
Purity (Absorbance): ≧ 95.0 % (as anhydrous)
Solubility in water: To pass test (clear, colorless to slightly yellow)
Water content: ≦ 10.0 %
NMR spectrum: Authentic
Handling and storage condition
Nitrogen substitution, Protect from moisture

Product Classification

Product Classification

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