20 Functional Organic Material

Carboxy-EG6-undecanethiol

Carboxy-EG<sub>6</sub>-undecanethiol

Self Assembled Monolayer Reagent

  • Product code
    C445  Carboxy-EG6-undecanethiol
  • CAS No.
    221222-49-7
  • Chemical name
    20-(11-Mercaptoundecanyloxy)-3,6,9,12,15,18-hexaoxaeicosanoic acid
  • MW
    C25H50O9S=526.73
Unit size Price Item Code
10 mg $283.00 C445-10
100 mg $603.00 C445-12
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Product Description

Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Carboxy-EG6-undecanethiol has 6 ethylene glycol units, 11 carbon Atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface suitable for biomaterial-labelings on the surface due to the improved hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays. To prepare a carboxy-EG6-SAM on a gold surface, hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute the number of carboxyl groups according to the density of the molecules being introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin and cytochrome C.

References

Open References

1. C. Pale-Grosdemange, E. S. Simon, K. L. Prime, and G. M. Whitesides, Anal. Chem., 1999, 71, 777.
2. A. Subramanian, J. Irudayaraj, and T. Ryan, Biosensors and Bioelectronics, 2006, 21, 998.
3. X. Qian, S. J. Metallo, I. S. Choi, H. Wu, M. N. Liang and G. M. Whitesides, Anal. Chem., 2002, 74, 1805.
4. M. Kyo, K.Usui-Aoki, H. Koga, Anal. Chem, 2005, 77, 7115.

Handling and storage condition

Specification
Appearance: Colorless to slightly yellow liquid
Purity (HPLC): ≧ 90.0 %
NMR spectrum: Authentic
Handling and storage condition
-20°C, Nitrogen substitution
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Product Classification

Product Classification

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