KMUS

$460.00

Chemical Name: N-(11-Maleimidoundecanoyloxy)succinimide
CAS: 87981-04-2

Appearance: White powder or crystalline powder
Purity: ≥90.0% (HPLC)
MW: 378.42, C19H26N2O6

Storage Condition: 0-5ºC, protect from moisture
Shipping Condition: ambient temperature

Clear
DescriptionApplicationS.D.S
Cross-linking Reaction

Product Description
Hetero-bifunctional cross-linking reagents have activated esters and maleimide reactive groups. These functional groups react with amines and sulfhydryl groups of proteins, respectively. Enzyme-labeled haptens are prepared using hetero-bifunctional cross-linking reagents such as EMCS or GMBS. The cross-linking reaction requires neutral pH and mild temperature because it is necessary to maintain enzyme activity and antibody titers in the cross-linking reaction. Hetero-bifunctional cross-linking reagents with 3, 5, 7, or 10 linear carbon chains are available. These linear aliphatic chains act as spacers between the two reactive sites and their water-soluble reagents. They are more stable than the aromatic cross-linking reagents such as succinimidyl-4-N-maleimidobenzoate in a wider pH range.

Conjugation of Macromolecules with Hetero-Bifunctional Cross-Linking Reagent

Hetero-bifunctional Reagents

Product Name Code Length (Å) Solvent
EMCS E018 9.4 DMSO
GMBS G005 6.9 Chloroform, DMF
HMCS H257 13.0 Acetonitrile
KMUS K214 16.7 Acetonitrile, Methyl alcohol

 

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Surface Chemistry

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