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2,3-Diaminonaphthalene (for NO detection) 2,3-Diaminonaphthalene (for NO detection), 2,3-Diaminonaphthalene [CAS: 771-97-1]

    Chemical Name: 2,3-Diaminonaphthalene CAS: 771-97-1Appearance: White or pale yellowish-brown powderSuitability for NO quantification: pass testMW: 158.20, C10H10N2Storage Condition: -20ºC, protect from lightShipping Condition: ambient temperatureProduct DescriptionThe Griess assay is a simple and popular method for detecting NO concentration. 2,3-Diaminonaphthalene (DAN) is a highly sensitive alternative to the Griess assay. The DAN method is 50-100 times more sensitive than the Griess assay:...

    2-PDS 2-PDS, 2,2 EDithiodipyridine [CAS: 2127-03-9]

      Chemical Name: 2,2'-Dithiodipyridine CAS: 2127-03-9Appearance: white or pale yellow powderMolar absorptivity: ≥14,000 at 235 nmMW: 220.32, C10H8N2S2Storage Condition : ambient temperatureShipping Condition : ambient temperature Fig 1. 2-PDS reaction with thiol compound ...

      3-Deoxyglucosone 3-Deoxyglucosone, 3-Deoxy-D-erythro-hexos-2-ulose [CAS: 4084-27-9]

        Chemical Name: 3-Deoxy-D-erythro-hexos-2-ulose CAS: 4084-27-9Appearance: white or pale yellow solidPurity: ≥99.0% (HPLC)MW: 162.14, C6H10O5Storage Condition: -20°CShipping Condition: protect from moisture with blue ice or dry iceProduct DescriptionAdvanced glycation end-products (AGEs) have been studied as one of the causes of diabetic complications. Several compounds have been identified as AGEs, including pyralline, pentosidine, imidazolone, and pyropyridine. Glyoxal and methylglyoxal are...

        3-Deoxyglucosone Detection Reagents 3-Deoxyglucosone Detection Reagents

          Contents of the kit DAN :10 mg x 1 3-DG/DAN adduct :1 mg x 1 Storage Condition : -20oC, protect from moistureShipping Condition: blue iceProduct DescriptionAdvanced glycation end-products (AGEs) have been studied as one of the causes of diabetic complications. Several compounds have been identified as AGEs, including pyralline, pentosidine, imidazolone, and pyropyridine. Glyoxal and methylglyoxal are reactive dicarbonyl compounds generated by glucose self-oxidation that are...

          4-PDS 4-PDS, 4,4 EDithiodipyridine [CAS: 2645-22-9]

            Chemical Name: 4,4'-Dithiodipyridine CAS: 2645-22-9Appearance: white or pale yellow powderMolar absorptivity: ≥14,000 at 235 nmMW: 220.32, C10H8N2S2 Storage Condition : ambient temperatureShipping Condition: ambient temperature Product Description2-PDS and 4-PDS are used for the photometric determination of thiol groups in biological samples. These compounds react with the thiol groups at pH 5 to form mercaptopyridine (Fig. 1 and 2). The maximum wavelengths of 2-Mercaptopyridine and...

            Anti-Nitroguanosine Monoclonal Antibody (clone#: NO2G52) Anti-Nitroguanosine Monoclonal Antibody clone#: NO2G52

              Appearance: Colorless to pale yellow sligtly turbid liquidAntibody titer: pass test Subtype: IgG1 (mouse BALB/c)Concentration: 1 mg/ml PBS solution; 0.1% ProClin as a preservativeStorage Condition: -20°CShipping Condition: with blue ice or dry iceProduct Description8-Nitroguanosine is a nitrated base of DNA and RNA. It is formed by peroxynitrite, which is generated from nitric oxide and superoxide anion radical. It is known that a large amount of nitric oxide molecules and superoxide anion,...

              Anti-Nitroguanosine Polyclonal Antibody Anti-Nitroguanosine Polyclonal Antibody

                Appearance: Colorless or Pale yellow sligtly turbid liquidAntibody titer: pass test Type: IgGConcentration: 200 μg per ml PBS solution;                    0.1% ProClin as a preservativeHost: Japanese rabbitStorage Condition: -20°CShipping Condition: with blue ice or dry iceProduct Description8-Nitroguanosine is a nitrated base of DNA and RNA. It is formed by peroxynitrite, which is generated from...

                BMPO BMPO, 5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide

                  Chemical Name: 5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide  Appearance: White to slightly yellowish white crystal or crystalline powderPurity: ≥99.0%MW: 199.25, C10H17NO3Storage condition: -20°C, protect from moisture Shipping condition: ambient temperatureChemical StructureProduct Description Spin trapping analysis is one of the most reliable techniques for detecting and identifying short-lived free radicals. The EPR (ESR) spin trap reagent detects both superoxide and...

                  Carboxy-PTIO Carboxy-PTIO, 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, sodium salt [CAS: 148819-93-6]

                    Chemical Name: 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, sodium salt CAS: 148819-93-6Appearance: Dark blue or black powderMW: 299.28, C14H16N2NaO4Storage Condition: -20ºC, protect from light, moisture and metal Shipping Condition: ambient temperatureProduct DescriptionCarboxy-PTIO is a stable, water-soluble organic radical that reacts with NO to form NO2· This reaction can be monitored by electron spin resonance (ESR). NO is an unstable molecule and has a...

                    DMPO DMPO5, 5-Dimethyl-1-Pyrroline-N-Oxide3317-61-1

                      Chemical Description: 5,5-Dimethyl-1-Pyrroline-N-OxideCAS: 3317-61-1Appearance: Colorless liquidPurity: ≥99.0%(GC)MW: 113.16, C6H11NODensity: 1.015g/mL at 25 °CStorage Condition: -20oC, protect from light and moisture Shipping Condition: Blue Ice Product Description Because of potential cancer risks and their age-promoting effects, free radicals in living bodies have become a frequently studied subject. DMPO is the most frequently used spin-trapping reagent for the study of free radicals. It...

                      DNA Damage Quantification Kit-AP Site Counting- DNA Damage Quantification Kit-AP Site Counting-

                        Contents of the Kit: 20 samples ARP Solution :250 μl x 1 tube DNA Binding Solution :10 ml x 1 bottle ARP-DNA Standard Solution :250 μl each Substrate Solution :10 ml x 1 bottle Filtration Tube :20 tubes TE Buffer :40 ml x 1 bottles Washing Buffer :1 packet HRP-Streptavidin :25 μl x 1 tubes 96-well Microplate :1 plate Storage Condition: 0-5ºCShipping Condition: ambient temperature or with blue iceRequired Equipment and Materialsmicroplate reader with 650 nm filter, incubator, microcentrifuge,...

                        DPPP DPPP, Diphenyl-1-pyrenylphosphine [CAS: 110954-36-4]

                          Chemical Name: Diphenyl-1-pyrenylphosphine CAS: 110954-36-4Appearance: slightly yellow powderPurity: ≥97% (HPLC)MW: 386.42, C28H19PStorage Condition : ambient temperature, protect from lightShipping Condition: ambient temperatureProduct DescriptionDPPP is a non-fluorescent triphenylphosphine compound. It reacts with hydroperoxide to generate DPPP oxide that emits fluorescence at 352 nm excitation and 380 nm emission wavelengths (Fig. 1). Post-column HPLC method is used to determine...

                          DTCS Na DTCS Na, N-(Dithiocarboxy)sarcosine, disodium salt, dihydrate [CAS: 13442-87-0]

                            Chemical Name: N-(Dithiocarboxy)sarcosine, disodium salt, dihydrate CAS: 13442-87-0Appearance: White or slightly yellow powderMW: 245.23, C4H5NNa2O2S2, 2H2OStorage Condition: 0-5ºC, protect from light and moisture Shipping Condition: ambient temperatureProduct DescriptionDiethyldithiocarbamate (DETC) is a good spin-trapping reagent for nitric oxide in vivo. However, DETC has not been widely utilized for NO detection in biological samples due to its poor water solubility. DTCS, an analog...

                            DTNB DTNB, 5,5 EDithiobis(2-nitrobenzoic acid) [CAS: 69-78-3]

                              Chemical Name: 5,5'-Dithiobis(2-nitrobenzoic acid)CAS: 69-78-3Appearance: pale yellow crystalline powderMolar absorptivity: ≥12,000 at 305 nmMW: 396.35, C14H8N2O8S2 Storage Condition : ambient temperatureShipping Condition: ambient temperature Product DescriptionDTNB is known as Ellman’s reagent. It is used for the colorimetric determination of thiol groups in biological samples. It is fairly soluble in water. Colorless DTNB is converted to yellow 5-Mercapto-2- nitrobenzoic acid in the...

                              GSSG/GSH Quantification Kit Glutathione,  GSSG/GSH Quantification Kit, measurement, detection, glutathione ratio, reduced, oxidized, antioxidant

                                --> Product DescriptionGlutathione (γ-L-glutamyl-L-cysteinylglycine) is a tripeptide present in the body, and it is involved in antioxidation, drug metabolism, and other as enzyme substrate of glutathione peroxidase, glutathione S-transferase, and thiol transferase, etc. Glutathione is usually present as reduced form (GSH), but GSH is converted into its oxidized form (GSSG) by stimulation such as oxidative stress. Therefore, the ratio of GSH and GSSG has been noted as index of oxidative...

                                Lactate Assay Kit-WST  L256, L256-05, L256-20, Lactate

                                  Lactate Assay Kit-WST can quantify lactate (the lower limit: 0.02 mmol/l), one of the glycolysis metabolites. Because the Lactate Assay Kit-WST corresponds to 96 well micro-plates, it allows for multiple samples to be measured at once. Lactate quantification has been widely used as a marker for monitoring changes in intracellular metabolic pathway in many different areas of cancer research. In recent years, there have been an increasing number of reports on using lactate as an indicator of...

                                  Liperfluo Liperfluo, lipid peroxide, Lipid hydroperoxide, Imaging, Detection, Kit, LPO, TBA, TBARS

                                    Product Description Liperfluo, a perylene derivative containing oligooxyethylene, is designed and exclusively developed by Dojindo for the detection of lipid peroxides. Liperfluo emits intense fluorescence by lipid peroxide specific oxidation in organic solvents such as ethanol. Among fluorescent probes that detect Reactive Oxygen Species(ROS), Liperfluo is the only compound that can specifically detect lipid peroxides. Since the excitation and emission wavelengths of the oxidized Liperfluo...

                                    MGD MGD, N-(Dithiocarbamoyl)-N-methyl-D-glucamine, sodium salt [CAS: 94161-07-6 (free acid)]

                                      Chemical Name: N-(Dithiocarbamoyl)-N-methyl-D-glucamine, sodium salt CAS: 94161-07-6 (free acid)Appearance: White crystalline powderPurity: ≥98.0% (HPLC)MW: 293.34, C8H16NNaO5S2Storage Condition: 0-5ºC, protect from moisture Shipping Condition:  ambient temperatureProduct DescriptionMGD is a highly water-soluble dithiocarbamate-type chelator that generates with complexes many transitional method such as Fe and Cu. The diethyldithiocarbamate-Fe2+ complex has been used for NO detection...

                                      MitoPeDPP MitoPeDPP, lipid peroxide, Lipid hydroperoxide, Imaging, Detection, Kit, LPO, TBA, TBARS

                                        Chemical Name: 3-[4-(Perylenylphenylphosphino)phenoxy]propyltriphenylphosphonium iodide Appearance: Yellow crystalline powder or solid Purity: ≥80.0% (HPLC) MW: 882.74, C53H41IOP2Storage Condition: 0-5ºC, protect from light Shipping Condition: ambient temperature Product DescriptionMitoPeDPP is a cell-membrane-permeable probe, Perylene-based dye. It specifically localizes in mitochondria due to the triphenylphosphonium moiety introduced. As the excitation and emission wavelength of MitoPeDPP...

                                        NOC 12 NOC 12, 1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazene [CAS: 146724-89-2]

                                          Chemical Name: 1-Hydroxy-2-oxo-3-(N-ethyl-2-aminoethyl)-3-ethyl-1-triazeneCAS: 146724-89-2Appearance: White powderPurity: ≥90% (HPLC)MW: 176.22, C6H16N4O2Storage Condition : -20ºC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC....

                                          NOC 18 NOC 18, 1-Hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene [CAS: 146724-94-9]

                                            Chemical Name: 1-Hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazeneCAS: 146724-94-9Appearance: White powderPurity: ≥90% (HPLC)MW: 163.18, C4H13N5O2Storage Condition : -20ºC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism...

                                            NOC 5 NOC 5, 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene [CAS: 146724-82-5]

                                              Chemical Name: 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene CAS: 146724-82-5Appearance: White powderPurity: ≥90% (HPLC)MW: 176.22, C6H16N4O2Storage Condition : -20ºC, protect from light and moistureShipping Condition : blue iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism...

                                              NOC 7 NOC 7, 1-Hydroxy-2-oxo-3-(N-methyl-3-aminopropyl)-3-methyl-1-triazene [CAS: 146724-84-7]

                                                Chemical Name: 1-Hydroxy-2-oxo-3-(N-methyl-3-aminopropyl)-3-methyl-1-triazene CAS: 146724-84-7Appearance: white powderPurity:≥90% (HPLC)MW: 162.19, C5H14N4O2Storage Condition : -20oC, protect from light and moistureShipping Condition: with blue ice or dry iceReaction of NO releaseProduct Description of NOC CompoundsNOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC....

                                                NOR 1 NOR 1, (+)-(E)-4-Methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexenamide [CAS: 163032-70-0]

                                                  Chemical Name: (+)-(E)-4-Methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexenamide CAS: 163032-70-0Appearance: White or slightly yellow powderPurity: ≥98.0% (HPLC)MW: 231.21, C8H13N3O5Storage Condition : -20ºC, protect from light and moistureShipping Condition: Ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety, they...

                                                  NOR 3 NOR 3, (+)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide [CAS: 138472-01-2]

                                                    Chemical Name: (+)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide CAS: 138472-01-2Appearance: White crystalline powderPurity: ≥98.0% (HPLC)MW: 215.21, C8H13N3O4Storage Condition : -20ºC, protect from light and moistureShipping Condition : ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety, they spontaneously...

                                                    NOR 4 NOR 4, (+)-N-{(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexene-1-yl}-3-pyridinecarboxamide [CAS: 162626-99-5]

                                                      Chemical Name: (+)-N-{(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexene-1-yl}-3-pyridinecarboxamide CAS: 162626-99-5Appearance: White or slightly yellow powderPurity: ≥98.0% (HPLC)MW: 306.32, C14H18N4O4Storage Condition : -20ºC, protect from light and moistureShipping Condition : ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or...

                                                      NOR 5 NOR 5, (+)-N-{(E)-4-Ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-heptenyl}-3-pyridinecarboxamide

                                                        Chemical Name: (+)-N-{(E)-4-Ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-heptenyl}-3-pyridinecarboxamideAppearance: White or slightly yellow powderPurity: ≥98.0% (HPLC)MW: 334.37, C16H22N4O4Storage Condition : -20ºC, protect from light and moistureShipping Condition : ambient temperatureReaction of NO releaseProduct Description of NOR CompoundsNORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety,...

                                                        S-Nitrosoglutathione S-Nitrosoglutathione, N-(N-L-?-Glutamyl-S-nitroso-L-cysteinyl)glycine [CAS: 57564-91-7]

                                                          Chemical Name: N-(N-L-γ-Glutamyl-S-nitroso-L-cysteinyl)glycine CAS: 57564-91-7Appearance: Pink powderPurity: ≥90.0% (HPLC)MW: 336.32, C10H16N4O7SStorage Condition: -20ºCShipping Condition: protect from moisture ambient temperatureReaction of NO releaseProduct Description of S-NitrosothiolsNitrosothiol compounds release NO and become disulfides under specific physiological conditions. While most of the S-nitrosothiol compounds are unstable, S-Nitrosoglutathione is exceptionally stable....

                                                          Si-DMA for Mitochondrial Singlet Oxygen Imaging MT05, MT05-10, Si-DMA for Mitochondrial Singlet Oxygen Imaging,

                                                            Storage Condition : Store at 0-5oC and protect from lightProduct Description Singlet oxygen (1O2) is one of the Reactive Oxygen Species (ROS). 1O2 is known to be a cause of spots and wrinkles of the skin due to its very strong oxidizing potential. In the field of cancer research, 1O2 is of a particular importance because of its key role in photodynamic therapy (PDT), an emerging anticancer treatment using photoirradiation and photosensitizers. For the detection of 1O2, the existing singlet...

                                                            SIN-1 SIN-1, 3-(4-Morpholinyl)sydnonimine, hydrochloride [CAS: 16142-27-1]

                                                              Chemical Name: 3-(4-Morpholinyl)sydnonimine, hydrochloride CAS: 16142-27-1Appearance: White or slightly yellowish needles or crystalline powderMW: 206.63, C6H11ClN4O2Storage Condition: -20ºC Shipping Condition: protect from light and moisture with blue ice or dry iceProduct DescriptionSIN-1, a metabolite of the vasodilator molsidomine, is utilized to separately estimate the effectiveness of NO and peroxynitrite with other NO donors. SIN-1 spontaneously decomposes in the presence of...

                                                              SOD Assay Kit-WST SOD Assay Kit-WST

                                                                Contents of the Kit: 500 tests WST solution :5 ml, 1 bottle Enzyme solution :100 μl, 1 vial Buffer solution :100 ml, 1 bottle Dilution buffer :50 ml,1 bottle Storage Condition: 0-5°CShipping Condition: ambient temperature or with blue iceRequired Equipment and MaterialsMicroplate reader with 450 nm filter, 37ºC incubator, 96-well clear plate, 10 μl and 200 μl adjustable pipettes, multi-channel pipetteProduct DescriptionSuperoxide dismutase (SOD), which catalyzes the dismutation of the...

                                                                Spy-LHP Spy-LHP, 2-(4-Diphenylphosphanyl-phenyl)-9-(1-hexyl-heptyl)-anthra[2,1,9-def,6,5,10-d’e’f’]diisoquinoline- 1,3,8,10-tetraone

                                                                  Chemical Name: 2-(4-Diphenylphosphanylphenyl)-9-(1-hexylheptyl)anthra[2,1,9-def,6,5,10-d’e’f’]diisoquinoline-1,3,8,10-tetraone Appearance: Reddish black crystalline powder or solidPurity: ≥90.0% (HPLC)MW: 832.96, C55H49N2O4PStorage Condition: ambient temperature, protect from lightShipping Condition: ambient temperatureProduct DescriptionSpy-LHP is a newly developed fluorescent probe for live cell imaging of phospholipid peroxide. There are several detection methods available for lipid...

                                                                  Total Glutathione Quantification Kit Total Glutathione Quantification Kit

                                                                    Contents of the Kit Enzyme solution  : 50 μl, 1 vial Substrate  : 2 vials Buffer solution  : 50 ml, 1 bottle Co-enzyme (lyophilized)  : 2 vials Standard GSH (lyophilized)  : 1 vial Storage Condition: 0-5ºCShipping Condition: ambient temperature or with blue iceRequired Equipment and Materialsmicroplate reader with 405 or 415 nm filter, 37ºC incubator, 96-well clear plate, 20 μl and 200 μl adjustable pipettes, multi-channel pipette Product DescriptionGlutathione (GSH)...