Since LDH release assay is a most time efficient and convenient method to evaluate large quantity of CAR T-cell samples/target cell effects (different E:T ratios and/or cells types ), this assay is suitable for primary screenings.
 Song, Y. et al (2017). Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo. Protein & Cell. doi:10.1007/s13238-017-0384-8