Dithiobis(C2-NTA)

Chelate Labeling Reagent
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Product codeD550 Dithiobis(C2-NTA)
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CAS No.1097730-65-8
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Chemical name3,3'-Dithiobis[N-(5-amino-5-carboxypentyl)propionamide-N',N'-diacetic acid] dihydrOchloride
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MWC26H44Cl2N4O14S2=771.68
| Unit size | Price | Item Code |
|---|---|---|
| 10 mg | Find your distributors | D550-10 |
| 50 mg | Find your distributors | D550-12 |
Description
Structural Formula

Product Description
Dithiobis(C2-NTA) is utilized for the modification of a gold surface to introduce NTA groups that can bind most heavy metal ions. It forms SAMs similar to the other alkanethiols. The SAMs prepared using Dithiobis(C2-NTA) are highly unidirectional due to its alkyl chain interactions. Ni(II)-NTA chelates are commonly used for Histidine-tagged (His-tag) protein purification or separation. Therefore, Ni(II)-NTA-coated gold can be used for His-tag protein analyses. Dithiobis(C2-NTA) is soluble in water and alcohol. It is also referred to as disulfide-NTA in some papers.
References
1)M. Murata, C. Gouda, K. Yano, S. Kuroki, T. Suzutani and Y. Katayama, "Piezo electric sensor for endocrine-disrupting chemicals using receptor-co-factor interaction",Anal. Sci., 2003, 19, 1355.
Handling and storage condition
| Appearance: | White to slightly yellow powder or crystal |
|---|---|
| Purity (Absorbance): | ≧ 95.0 % (as anhydrous) |
| Solubility in water: | To pass test (clear, colorless to slightly yellow) |
| Water content: | ≦ 10.0 % |
| NMR spectrum: | Authentic |
| Nitrogen substitution, Protect from moisture |






