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8-Hydroxy-1-octanethiol

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 Item # Description/Size Availability Qty Break Price Quantity Subscription Frequency
H338-10
10 mg
5-10 business days $126.00
H338-12
100 mg
5-10 business days $351.00

*Estimated. Exact shipping date will be notified.  
For Research Use Only Products   

MSDS
Chemical Name: 8-Hydroxy-1-octanethiol
CAS: 33065-54-2

Appearance: coloress or slightly yellow liquid
Purity: >98.0% (GC)
MW:
162.29, C8H18OS

Storage Condition: -20oC, protect from metal
Shipping Condition: ambient temperature



Chemical Formula


Product Description
Hydroxyalkanethiols are utilized as dilution reagents on a gold surface to control the density of reactive groups, or as blocking agents to prevent non-specific binding of analytes on the surface. Newly developed 16-Hydroxy-1-hexadecanethiol has a 16-carbon chain which is the longest alkanethiol available in the market among hydroxyalkanethiols. In all, there are a total of 6 different hydroxyalkanethiols including Hydroxy-EG6-undecanethiol and Hydroxy-EG3-undecanethiol available for gold surface modification. 16-Hydroxy-1-hexadecanethiol is used to prepare a homogeneous and highly oriented SAM when 16-Amino-1-hexadecanethiol or 15-Carboxy-1-pentadecanethiol is applied. Herne and his co-workers fabricated mixed SAMs of thiol-derivatized singlestranded DNA (HS-ss-DNA) and 6-Hydroxy-1-hexanethiol on a gold surface that prevented non-specific adsorption of HS-ss-DNA. Perez-Luna and others made mixed SAMs of biotin-terminated thiol and 11-hydroxy-1-undecanethiol on a gold surface. They prevented non-specific adsorption of wild type streptavidin and streptavidin mutants. Dubrovsky and coworkers controlled the non-specific adsorption of protein on the surface of gold-coated silicagel using 11-Hydroxy-1-undecanethiol. They mentioned the usefulness of gold-coated silica gel for the preparation of well-defined, surface-functionalized supports for biological assay.

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