4, 4 E Dithiodibutyric acid

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4, 4 E Dithiodibutyric acid (500mg) - D524-10

Item #	Description/Size	Availability	Qty Break	Price	Quantity
D524-10	500 mg	5-10 business days	1	$186.00

*Estimated. Exact shipping date will be notified.
For Research Use Only Products

Application: SAM preparation, carboxylate coating

Description
Application

Chemical Name: 4,4 EDithiodibutyric acid
CAS: 2906-60-7

Appearance: White Crystalline powder
Purity: ≥97.0% (HPLC)
MW: 238.33, C₈H₁₄O₄S₂

Storage Condition: ambient temperature, protect from metal
Shipping Condition: ambient temperature

Structural Formula

Product Description of Carboxyallanedisulfides

Product Description of Carboxyallanedisulfides Carboxyalkyldisulfides are oxidized carboxyalkanethiols. They form SAMs similar to the carboxyalkanethiols, but are more stable than thiols. Kanayama and others formed SAMs of 4,4’-dithiodibutyric acid on gold colloids or gold electrodes and introduced phenylboronic acid moieties to its terminus. They succeeded in recognizing various sugars by surface-enhanced Raman spectroscopy (SERS) and cyclic voltammetry (CV) using these SAMs. Takagi and coworkers fixed dinitrophenyl (DNP) groups on carboxyalkyl-disulfide SAMs. They detected an anti-DNP antibody by electrical impedance measurement. This technique could be applied to impedimetric sensing of proteins. Delamarche and his coworkers fabricated 10-carboxydecyl disulfide SAMs on a gold substrate and introduced a photoactivatable benzophenone moiety to the termini. After attaching a protein (IgG), it was tested by a variety of characterization techniques (including ellipsometry, Xray photoelectron spectroscopy and AFM).

References
1. N. Kanayama and H. Kitano, Interfacial Recognition of Sugar by Boronic acid-Carrying self-Assembled Monolayers, Langmuir, 2000, 16, 577.
2. R. D. Vaughan, C. K. O’Sullivan and G. G. Guilbault, Sulfer based Self-assembled Monolayers(SAM’s) on Piezoelectric Crystals for Immunosensor development, Fresenius J. Anal. Chem., 1999, 364, 54.
3. H. Taira, K. Nakano, M. Maeda and M. Takagi, Electrode Modification by Long-Chain,Dialkyl Disulfide Reagent Having Terminal Dinitrophemyl Group and Its Application to Impedimetric Immunosensors. Anal. Sci., 1993, 9, 199.
4. E. Delamarche, G. Sundarababu, H. Biebuyck, B. Michel, Ch. Gerber, H. Sigrist, H. Wolf, H. Ringsdorf, N. Xanthopoulos and H. J. Mathieu, Immobilization of Antibodies on a Photoactive Self-Assembled Monolater on Gold, Langmuir, 1996, 12, 1997.